pharmaceutical-powder-compattion-technology

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Pharmaceutical Powder Compaction Technology Second Edition

Author : Metin Çelik
ISBN : 9781420089189
Genre : Medical
File Size : 34. 98 MB
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Compaction of powder constituents—both active ingredient and excipients—is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients

Pharmaceutical Powder Compaction Technology Second Edition

Author : Metin Çelik
ISBN : 142008917X
Genre : Medical
File Size : 68. 45 MB
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Compaction of powder constituents—both active ingredient and excipients—is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients

Pharmaceutical Powder Compaction Technology

Author : Taylor & Francis Group
ISBN : 0367783770
Genre :
File Size : 29. 75 MB
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Pharmaceutical Powder Compattion Technology

Author : Goran Alderborn
ISBN : 0367401576
Genre :
File Size : 21. 29 MB
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This unique reference examines the modern pharmaceutical compacting techniques used to form tablets out of powders-describing the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles.

Pharmaceutical Powder Compattion Technology

Author : Goran Alderborn
ISBN : 0824793765
Genre : Medical
File Size : 32. 22 MB
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This unique reference examines the modern pharmaceutical compacting techniques used to form tablets out of powders-describing the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles.

Developing Solid Oral Dosage Forms

Author : Yihong Qiu
ISBN : 008093272X
Genre : Medical
File Size : 70. 89 MB
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Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies

Encyclopedia Of Pharmaceutical Technology

Author : James Swarbrick
ISBN : 9781439808238
Genre : Medical
File Size : 67. 78 MB
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Presenting authoritative and engaging articles on all aspects of drug development, dosage, manufacturing, and regulation, this Third Edition enables the pharmaceutical specialist and novice alike to keep abreast of developments in this rapidly evolving and highly competitive field. A dependable reference tool and constant companion for years to com

Aulton S Pharmaceutics E Book

Author : Kevin M.G. Taylor
ISBN : 9780702081569
Genre : Medical
File Size : 55. 89 MB
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The essential pharmaceutics textbook One of the world’s best-known texts on pharmaceutics, Aulton's Pharmaceutics offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees. Thoroughly revised, updated and extended by experts in their fields and edited by Professors Kevin Taylor and Michael Aulton, this new edition includes the science of formulation, pharmaceutical manufacturing and drug delivery. All aspects of pharmaceutics are covered in a clear and readily accessible way and extensively illustrated throughout, providing an essential companion to the entire pharmaceutics curriculum from day one until the end of the course. Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation Designed and written for newcomers to the design and manufacture of dosage forms Relevant pharmaceutical science covered throughout Includes the science of formulation and drug delivery Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines Key points boxes throughout Over 400 online multiple choice questions

Modelling Of Powder Die Compaction

Author : Peter R. Brewin
ISBN : 9781846280993
Genre : Technology & Engineering
File Size : 82. 90 MB
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Manufacture of components from powders frequently requires a compaction step. Modelling of Powder Die Compaction presents a number of case studies that have been developed to test compaction models. It will be bought by researchers involved in developing models of powder compaction as well as by those working in industry, either using powder compaction to make products or using products made by powder compaction.

Pharmaceutical Capsules

Author : Fridrun Podczeck
ISBN : 0853695687
Genre : Business & Economics
File Size : 70. 88 MB
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Updated and expanded second edition covers all aspects of capsule technology, including history, standards, methods and equipment used in manufacture, filling, printing, weighing, cleaning and inspecting of both hard and soft capsules.

Particle Particle Adhesion In Pharmaceutical Powder Handling

Author : Fridrun Podczeck
ISBN : 9781783262311
Genre : Medical
File Size : 24. 39 MB
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This monograph describes the physical principles of adhesion between particles and surfaces. These principles are applied to pharmaceutical processes involved in the manufacture of solid dosage forms such as powders, granules, tablets and dry powder inhalations. To help in the understanding of these systems, physical properties of solid surfaces, and an introduction to the theory of friction is given. Techniques for measuring particle adhesion and fracture mechanical properties of powders are introduced, as far as these are relevant to the processes discussed. The philosophy of the book deviates from that of standard pharmaceutical textbooks, in that it focuses primarily on physical principles involved in the manufacture of dosage forms rather than describing these processes purely by observation.

Aulton S Pharmaceutics

Author : Michael E. Aulton
ISBN : 9780702042904
Genre : Medical
File Size : 61. 36 MB
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Pharmaceutics is one of the most diverse subject areas in all of pharmaceutical science. In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms or medicines. An understanding of pharmaceutics is therefore vital for all pharmacists and those pharmaceutical scientists who are involved with converting a drug or a potential drug into a medicine that can be delivered safely, effectively and conveniently to the patient. Now in its fourth edition, this best-selling textbook in pharmaceutics has been brought completely up to date to reflect the rapid advances in delivery methodologies by eye and injection, advances in drug formulations and delivery methods for special groups (such as children and the elderly), nanomedicine, and pharmacognosy. At the same time the editors have striven to maintain the accessibility of the text for students of pharmacy, preserving the balance between being a suitably pitched introductory text and a clear reflection of the state of the art. provides a logical, comprehensive account of drug design and manufacture includes the science of formulation and drug delivery designed and written for newcomers to the design of dosage forms New to this edition New editor: Kevin Taylor, Professor of Clinical Pharmaceutics, School of Pharmacy, University of London. Twenty-two new contributors. Six new chapters covering parenteral and ocular delivery; design and administration of medicines for the children and elderly; the latest in plant medicines; nanotechnology and nanomedicines, and the delivery of biopharmaceuticals. Thoroughly revised and updated throughout.

Pharmaceutical Dosage Forms

Author : Larry L. Augsburger
ISBN : 9781841849775
Genre : Medical
File Size : 75. 1 MB
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Pharmaceutical Dosage Forms: Capsules covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation.

Handbook Of Pharmaceutical Granulation Technology

Author : Dilip M. Parikh
ISBN : 9781000366389
Genre : Medical
File Size : 76. 15 MB
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This fully revised edition of Handbook of Pharmaceutical Granulation Technology covers the rapid advances in the science of agglomeration, process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe. Learn from more than 50 global subject matter experts who share their years of experience in areas ranging from drug delivery and pharmaceutical technology to advances in nanotechnology. Every pharmaceutical scientist should own a copy of this fourth edition resource. Key Features: Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies

Advances In Food And Nutrition Research

Author : Steve Taylor
ISBN : 0080490123
Genre : Technology & Engineering
File Size : 20. 30 MB
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Advances in Food and Nutrition Research is an eclectic serial established in 1948. The serial recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Contributions detail the scientific developments in the broad areas encompassed by the fields of food science and nutrition and are intended to ensure that food scientists in academia and industry, as well as professional nutritionists and dieticians, are kept informed concerning emerging research and developments in these important disciplines. Series established since 1948 Advisory Board consists of 8 respected scientists Unique series as it combines food science and nutrition research

Handbook Of Modern Pharmaceutical Analysis

Author : Satinder Ahuja
ISBN : 0123759811
Genre : Medical
File Size : 30. 87 MB
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Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS

Modern Pharmaceutics Two Volume Set

Author : Alexander T. Florence
ISBN : 9781420065718
Genre : Medical
File Size : 38. 77 MB
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This new edition brings you up-to-date on the role of pharmaceutics and its future paradigms in the design of medicines. Contributions from over 30 international thought leaders cover the core disciplines of pharmaceutics and the impact of biotechnology, gene therapy, and cell therapy on current findings. Modern Pharmaceutics helps you stay current

Particle Technology And Engineering

Author : Jonathan P.K. Seville
ISBN : 9780080983448
Genre : Technology & Engineering
File Size : 77. 81 MB
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Particle Technology and Engineering presents the basic knowledge and fundamental concepts that are needed by engineers dealing with particles and powders. The book provides a comprehensive reference and introduction to the topic, ranging from single particle characterization to bulk powder properties, from particle-particle interaction to particle-fluid interaction, from fundamental mechanics to advanced computational mechanics for particle and powder systems. The content focuses on fundamental concepts, mechanistic analysis and computational approaches. The first six chapters present basic information on properties of single particles and powder systems and their characterisation (covering the fundamental characteristics of bulk solids (powders) and building an understanding of density, surface area, porosity, and flow), as well as particle-fluid interactions, gas-solid and liquid-solid systems, with applications in fluidization and pneumatic conveying. The last four chapters have an emphasis on the mechanics of particle and powder systems, including the mechanical behaviour of powder systems during storage and flow, contact mechanics of particles, discrete element methods for modelling particle systems, and finite element methods for analysing powder systems. This thorough guide is beneficial to undergraduates in chemical and other types of engineering, to chemical and process engineers in industry, and early stage researchers. It also provides a reference to experienced researchers on mathematical and mechanistic analysis of particulate systems, and on advanced computational methods. Provides a simple introduction to core topics in particle technology: characterisation of particles and powders: interaction between particles, gases and liquids; and some useful examples of gas-solid and liquid-solid systems Introduces the principles and applications of two useful computational approaches: discrete element modelling and finite element modelling Enables engineers to build their knowledge and skills and to enhance their mechanistic understanding of particulate systems

Pharmaceutical Crystals

Author : Tonglei Li
ISBN : 9781119046349
Genre : Science
File Size : 44. 52 MB
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An important resource that puts the focus on understanding and handling of organic crystals in drug development Since a majority of pharmaceutical solid-state materials are organic crystals, their handling and processing are critical aspects of drug development. Pharmaceutical Crystals: Science and Engineering offers an introduction to and thorough coverage of organic crystals, and explores the essential role they play in drug development and manufacturing. Written contributions from leading researchers and practitioners in the field, this vital resource provides the fundamental knowledge and explains the connection between pharmaceutically relevant properties and the structure of a crystal. Comprehensive in scope, the text covers a range of topics including: crystallization, molecular interactions, polymorphism, analytical methods, processing, and chemical stability. The authors clearly show how to find solutions for pharmaceutical form selection and crystallization processes. Designed to be an accessible guide, this book represents a valuable resource for improving the drug development process of small drug molecules. This important text: Includes the most important aspects of solid-state organic chemistry and its role in drug development Offers solutions for pharmaceutical form selection and crystallization processes Contains a balance between the scientific fundamental and pharmaceutical applications Presents coverage of crystallography, molecular interactions, polymorphism, analytical methods, processing, and chemical stability Written for both practicing pharmaceutical scientists, engineers, and senior undergraduate and graduate students studying pharmaceutical solid-state materials, Pharmaceutical Crystals: Science and Engineering is a reference and textbook for understanding, producing, analyzing, and designing organic crystals which is an imperative skill to master for anyone working in the field.

Pharmaceutical Dosage Forms Tablets

Author : Larry L. Augsburger
ISBN : 9781420063868
Genre : Medical
File Size : 58. 59 MB
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The ultimate goal of drug product development is to design a system that maximizes the therapeutic potential of the drug substance and facilitates its access to patients. Pharmaceutical Dosage Forms: Tablets, Third Edition is a comprehensive resource of the design, formulation, manufacture, and evaluation of the tablet dosage form, an

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