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Mechanisms Of Dna Recombination And Genome Rearrangements Methods To Study Homologous Recombination

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ISBN : 9780128144305
Genre : Science
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Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts. Contributions by the leading experts in the field of DNA repair, recombination, replication and genome stability Documents cutting edge methods

Genetic Recombination

Author : H. L. K. Whitehouse
ISBN : UOM:39015010181892
Genre : Science
File Size : 31. 74 MB
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A comprehensive survey of important research into genetic recombination, including consideration of bacteria and their viruses as well as fungi and other higher organisms. Discusses current theories of mechanisms of recombination and examines non-homologous recombination, which differs fundamentally from the ``normal'' mechanism in not requiring correspondence of nucleotide sequence. Includes a glossary of technical terms.

Dna Replication Recombination And Repair

Author : Fumio Hanaoka
ISBN : 9784431558736
Genre : Science
File Size : 64. 68 MB
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This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.

Mechanisms Of Eukaryotic Dna Recombination

Author : Max E Gottesman
ISBN : 9781483274089
Genre : Science
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Mechanisms of Eukaryotic DNA Recombination is a collection of papers that discusses advances in eukaryotic genetic recombination. Papers address issues in eukaryotic genetic recombination, particularly DNA integration in mammalian genomes, genetic recombination in Drosophila or Caenorhabditis; the manipulation of the mouse genome; genome organization; and genetic recombination in protozoa. One paper discusses chromatid interactions during intrachromosomal recombination in mammalian cells, namely, intrachromatid and sister chromatid. Another paper analyzes the implication for chromosomal recombination and gene targeting; results on extrachromosomal recombination show that circles are inefficient substrates for recombination even if only one of two substrates in an intermolecular reaction is circular. One author discusses the genetics and molecular biology of recombination, citing the work of Watson and Crick, stating that crossing-over occurs between genes (not within them). He also explains that the formation and resolution of recombination intermediaries depend on enzyme or other proteins. This book will prove invaluable to cellular biologists, microbiologists, and researchers engaged in genetics and general biology.

Molecular Genetics Of Recombination

Author : Andrés Aguilera
ISBN : 9783540710219
Genre : Science
File Size : 71. 52 MB
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This work offers a fascinating insight into a crucial genetic process. Recombination is, quite simply, one of the most important topics in contemporary biology. This book is a totally comprehensive treatment of the subject, summarizing all existing views on the topic and at the same time putting them into context. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field.

Studies On The Mechanism Of Red Mediated Recombination In Bacteriophage Lambda

Author : Gordon James Vance Makin
ISBN : WISC:89097322192
Genre : Bacteriophage lambda
File Size : 86. 47 MB
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Studies On Mechanisms Of Site Specific Recombination And Dna Structure In Vitro

Author : Robert Lawrence Weinberg
ISBN : UCAL:C2792607
Genre :
File Size : 53. 32 MB
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Advances In Biophysics

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ISBN : OCLC:929855323
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File Size : 49. 95 MB
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Biochemical Mechanisms Of Genetic Recombination

Author : Kirsten Rachel Benjamin
ISBN : UCAL:C3322621
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Mechanisms Of Yeast Recombination

Author : Amar Klar
ISBN : UCAL:B5018603
Genre : Science
File Size : 54. 94 MB
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Dna Pairing Mechanisms During Homologous Recombination Events Promoted By The Escherichia Coli Reca And Saccharomyces Cerevisiae Rad51 Proteins

Author : Kevin Peter Rice
ISBN : WISC:89075864884
Genre :
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Radio Engineering Electronic Physics

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ISBN : UOM:39015029619627
Genre : Electronics
File Size : 49. 11 MB
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Recombination Mechanisms In Ingan Quantum Wells

Author : Noad Asaf Shapiro
ISBN : UCAL:C3445645
Genre :
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Journal Of Experimental And Theoretical Physics

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ISBN : CHI:82257647
Genre : Physics
File Size : 42. 28 MB
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Mechanisms And Consequences Of Dna Damage Processing

Author : Errol C. Friedberg
ISBN : UOM:39015013207215
Genre : ADN - Réparation - Congrès
File Size : 31. 72 MB
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Research Awards Index

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ISBN : STANFORD:36105119623838
Genre : Medicine
File Size : 65. 17 MB
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Kinetics And Catalysis

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ISBN : UCSD:31822017855289
Genre : Catalysis
File Size : 61. 66 MB
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Topological Mechanism Of Site Specific Recombination By Tn3 Resolvase

Author : Jan Melise Dungan
ISBN : UCAL:$C72982
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Dna Repair Mechanisms

Author : Jean-Michel H. Vos
ISBN : WISC:89055819437
Genre : Science
File Size : 36. 91 MB
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Research Grants Index

Author : National Institutes of Health (U.S.). Division of Research Grants
ISBN : UOM:39015072175394
Genre : Medicine
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