cognitive-impairment

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Mild Cognitive Impairment

Author : Holly A. Tuokko
ISBN : 9781134953820
Genre : Psychology
File Size : 90. 40 MB
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Mild Cognitive Impairment (MCI) has been identified as an important clinical transition between normal aging and the early stages of Alzheimer's disease (AD). Since treatments for AD are most likely to be most effective early in the course of the disease, MCI has become a topic of great importance and has been investigated in different populations of interest in many countries. This book brings together these differing perspectives on MCI for the first time. This volume provides a comprehensive resource for clinicians, researchers, and students involved in the study, diagnosis, treatment, and rehabilitation of people with MCI. Clinical investigators initially defined mild cognitive impairment (MCI) as a transitional condition between normal aging and the early stages of Alzheimer’s disease (AD). Because the prevalence of AD increases with age and very large numbers of older adults are affected worldwide, these clinicians saw a pressing need to identify AD as early as possible. It is at this very early stage in the disease course that treatments to slow the progress and control symptoms are likely to be most effective. Since the first introduction of MCI, research interest has grown exponentially, and the utility of the concept has been investigated from a variety of perspectives in different populations of interest (e.g., clinical samples, volunteers, population-based screening) in many different countries. Much variability in findings has resulted. Although it has been acknowledged that the differences observed between samples may be ‘legitimate variations’, there has been no attempt to understand what it is we have learned about MCI (i.e., common features and differences) from each of these perspectives. This book brings together information about MCI in different populations from around the world. Mild Cognitive Impairment will be an important resource for any clinician, researcher, or student involved in the study, detection, treatment, and rehabilitation of people with MCI.

Cognitive Impairment In Schizophrenia

Author : Philip D. Harvey
ISBN : 9781139619554
Genre : Medical
File Size : 47. 9 MB
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Although the precise mechanisms and pathways of schizophrenia remain something of a mystery, there is little dispute that cognitive deficits present as some of the clearest and most debilitating symptoms of the disease. This book describes the characteristics of cognitive deficits in schizophrenia, functional implications, the course of impairments, the genetic and biological contributions and reviews management options, including neuropsychological, psychological and pharmacological techniques. Chapters are written by leading experts in the field, in an accessible and highly informative style, ensuring the content is clinically relevant. State-of-the-art information about new developments in the treatment of related features of the illness, such as disability, is provided. The wide ranging focus of this volume will appeal to clinicians and academic researchers working with patients impaired by severe mental illness.

Vascular Cognitive Impairment In Clinical Practice

Author : Lars-Olof Wahlund
ISBN : 9780521875370
Genre : Medical
File Size : 54. 59 MB
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Vascular cognitive impairment is the second most common cause of dementia after Alzheimer's disease and is expected to grow in prevalence with the aging global population. The purpose of this authoritative book is to give a broad clinical perspective on vascular cognitive impairment and thus create a foundation for the implementation of good dementia care. The book focuses on pathophysiology, diagnosis, treatment and prevention. It demonstrates the underlying causes of the disorder, such as the manner in which vascular risk-factors influence the onset of vascular cognitive impairment. The concept of mixed forms of vascular dementia, Alzheimer's dementia and other vascular diseases is discussed as well as the influence of vascular changes with regard to the onset of Alzheimer's disease. The detailed section on pathophysiology will enhance clinicians' understanding of this complex disorder. Finally there is a section on pharmacological and neuropsychological treatment of cognitive and psychiatric symptoms.

Living With Mild Cognitive Impairment

Author : Nicole D. Anderson
ISBN : 9780199978908
Genre : Psychology
File Size : 21. 52 MB
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One in ten adults over 65 has some form of mild cognitive impairment or MCI--thinking problems that go beyond those associated with normal aging, but that fall short of the serious impairments experienced by people with Alzheimer's Disease and other dementias. This is the first book written specifically for individuals with MCI, for their loved ones, and for the health care professionals who treat them. Written by three clinicians and researchers who have devoted their careers to MCI patients, this book provides up-to-date and reliable information on the nature of this disorder, how it may affect people, and what can be done about it. The authors explain how MCI is diagnosed and treated and they offer advice on how to improve cognitive health through diet and exercise, through social engagement, and through the use of practical, effective memory strategies. Throughout, case studies illustrate the real-life issues facing people living with MCI. The book includes "Questions to Ask Your Doctor," recommended readings and links to relevant websites, and worksheets to guide readers through healthy lifestyle changes.

Animal Models Of Cognitive Impairment

Author : Edward D. Levin
ISBN : 9781420004335
Genre : Science
File Size : 80. 86 MB
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The costs associated with a drug’s clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications. The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer’s, schizophrenia, and ADHD. Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.

Cognitive Impairment And Dementia In Parkinson S Disease

Author : Murat Emre
ISBN : 9780191015748
Genre : Medical
File Size : 54. 56 MB
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Parkinson's disease has long been perceived as a pure motor disorder, partly due to its initial description by James Parkinson, who suggested that "senses and intellect remain intact", and partly due to the fact that patients with PD did not survive long, before effective treatment became available. As the survival time of patients with Parkinson's disease has substantially increased due to modern treatment, it has become apparent that cognitive deficits and dementia are also frequent features, especially in elderly patients. With the progression of the disease and age, dementia develops in a substantial number of patients and constitutes a major therapeutic challenge. Dementia has thus increasingly been the focus of research and practice in recent years and a large body of knowledge has been accumulated. Despite these developments there has been no single volume dedicated to this topic. This book provides an extensive overview of the current status of knowledge pertaining to cognitive impairment and dementia associated with Parkinson's disease, intended as a reference book for general neurologists, neurology residents and also those with a special interest in movement disorders. In this edited volume experts in the field describe in detail all aspects of cognitive impairment and dementia in Parkinson's disease, including epidemiology, spectrum of clinical features, pathology, neurochemistry and genetics, findings in auxiliary investigations, relation to other neurodegenerative disorders, diagnostic process and management, and rounded up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and heavily referenced to encompass all relevant literature.

Cognitive Impairment And Dementia An Update

Author : João Massano
ISBN : 9782889190652
Genre :
File Size : 41. 82 MB
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Cognitive impairment and dementia afflict a large number of people worldwide, being a major source of disability and loss of income. The amount of research on this subject is extensive, covering from basic to translational and clinical aspects. Therefore, it is hard to keep up with the amount of publications and novelties in this field, especially for the busy clinician. On the other hand, basic scientists often find it difficult to explore the vast clinical literature on this matter, as well as understand the clinical features of these disorders and to define the current research needs and directions. The main aim of this Frontiers Research Topic is to provide a solid and valuable platform of scientific synthesis regarding the current knowledge and literature on this theme, including clinical features, current and emergent diagnostic strategies, management (both present and future), and other important issues pertaining to cognitive impairment and dementia.

Mild Cognitive Impairment

Author : Ronald C. Petersen
ISBN : 0198028741
Genre : Medical
File Size : 80. 46 MB
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What are the boundary zones between normal aging and Alzheimer's disease (AD)? Are many elderly people whom we regard as normal actually in the early stages of AD? Alzheimer's disease does not develop overnight; the early phases may last for years or even decades. Recently, clinical investigators have identified a transitional condition between normal aging and and very early Alzheimer's disease that they have called mild cognitive impairment, or MCI. This term typically refers to memory impairment beyond what one would expect in individuals of a given age whose other abilities to function in daily life are well preserved. Persons who meet the criteria for mild cognitive impairment have an increased risk of progressing to Alzheimer's disease in the near future. Though many questions about this condition and its underlying neuropathology remain open, full clinical trials are currently underway worldwide aimed at preventing the progression from MCI to Alzheimer's disease. This book addresses the spectrum of issues involved in mild cognitive impairment, and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment. It is intended for clinicians, researchers, and students interested in aging and cognition, among them neurologists, psychiatrists, geriatricians, clinical psychologists, and neuropsychologists.

Cognitive Impairment In Major Depressive Disorder

Author : Roger S. McIntyre
ISBN : 9781107074583
Genre : Medical
File Size : 81. 46 MB
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The first book to comprehensively assemble research, clinical, and public policy perspectives on cognitive dysfunction in major depressive disorder.

Diagnosis Of Dementia And Cognitive Impairment

Author : Andrew J. Larner
ISBN : 9783039218844
Genre : Medical
File Size : 23. 20 MB
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In this special issue of Diagnostics, expert contributors have produced up-to-date research studies and reviews on various topics related to the diagnosis of dementia and cognitive impairment. The methods of the assessments discussed extend from simple neurological signs, which may be elicited in the clinical encounter, through cognitive screening instruments, to sophisticated analyses of neuroimaging and cerebrospinal fluid biomarkers of disease. It is hoped that these various methods may facilitate earlier diagnosis of dementia and its subtypes, and provide differential diagnosis of depression and functional cognitive disorders, as a prelude to meaningful interventions.

Cognitive Impairment And Depression In Older Patients

Author : Martin Steinberg
ISBN : 9780199959556
Genre : Medical
File Size : 90. 43 MB
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Cognitive impairment and depression in older people have challenged clinicians and families for decades. These conditions affect well over half of people after age 65 with an incidence that increases with advancing age. Many factors account for this including the aging brain, loss of purpose, social isolation, personal losses, medical morbidity, and others. The mortality, disability, and burdens associated with these conditions, affecting patients, family members, and society at large are legion. Advances in epidemiology, brain science, therapeutics, and in service delivery continue to improve our understanding of these conditions, their causes, and the best ways to treat them. Despite this cognitive impairment and depression in later life remain underdiagnosed and undertreated in the United States. This book provides a single source for clinicians who treat older people to become more effective in the evaluation, diagnosis, and treatment of these challenging late life conditions. It offers a pragmatic, easy-to-use, resource that guides clinicians in how to best evaluate and treat older people with depression and cognitive impairment.

Vascular Disease Alzheimer S Disease And Mild Cognitive Impairment

Author : David J. Libon
ISBN : 9780190668556
Genre : Psychology
File Size : 71. 33 MB
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Alzheimer's disease (AD) and vascular dementia (VaD) are commonly viewed as the first and second most common types of dementia, respectively. The traditional paradigm has been to view and treat each illness as a separate entity with a separate pathophysiology. However, clinical and pathological studies suggest that the boundary separating AD and VaD, as well as their mild cognitive impairment (MCI) analogs, is not well defined. Thus, there is increased interest in viewing these diseases along a spectrum because of the significant overlap in the characterization and diagnosis of AD, VaD, and MCI. The focus of this edited volume is to examine how AD and VaD, as well as their MCI analogs, are best viewed as a heterogeneous, intersecting, if not a continuous disease state rather than separate, distinct entities. This book examines this approach by providing empirically based evidence, reviews of the literature, and chapters by key leaders in the field and will be of interest to clinical neuropsychologists and anyone studying or treating dementia in its many forms.

Assessment Of Feigned Cognitive Impairment Second Edition

Author : Kyle Brauer Boone
ISBN : 9781462545551
Genre : Law
File Size : 90. 55 MB
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The go-to resource for clinical and forensic practice has now been significantly revised with 85% new material, reflecting the tremendous growth of the field. Leading authorities synthesize the state of the science on symptom feigning in cognitive testing and present evidence-based recommendations for distinguishing between credible and noncredible performance. A wide range of performance validity tests (PVTs) and symptom validity tests (SVTs) are critically reviewed and guidelines provided for applying them across differing cognitive domains and medical, neurological, and psychiatric conditions. The book also covers validity testing in forensic settings and with particular populations, such as ethnic and linguistic minority group members. New to This Edition *Numerous new authors, a greatly expanded range of topics, and the latest data throughout. *"Clinical primer" chapter on how to select and interpret appropriate PVTs. *Chapters on methods for validity testing in visual–spatial, processing speed, and language domains and with cognitive screening instruments and personality inventories. *Chapter on methods for interpreting multiple PVTs in combination. *Chapters on additional populations (military personnel, children and adolescents) and clinical problems (dementia, somatoform/conversion disorder). *Chapters on research methods for validating PVTs, base rates of feigned mild traumatic brain injury, and more.

Mild Cognitive Impairment An Issue Of Clinics In Geriatric Medicine

Author : Birju Patel
ISBN : 9780323242240
Genre : Medical
File Size : 46. 44 MB
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This issue of Clinics in Geriatric Medicine features expert clinical reviews on Mild Cognitive Impairment which includes current information on topics such as Overview of Mild Cognitive Impairment, Aging and Cognition, Classification and Epidemiology of Mild Cognitive Impairment, Neuropsychiatric Symptoms of Mild Cognitive Impairment, Clinical Evaluation of Early Cognitive Symptoms, Emerging Biomarkers Relating to Cognition, Imaging Modalities in Evaluation of Cognition, Current Management Decisions in Mild Cognitive Impairment, Risk Factors for Progression to Dementia, Dealing with Mild Cognitive Impairment: Help for Patients and Caregivers.

Mild Cognitive Impairment And Dementia

Author : Glenn E. Smith
ISBN : 9780199909155
Genre : Psychology
File Size : 78. 58 MB
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In 2011, National Institute on Aging and Alzheimer's Association joint task forces released proposed criteria for Alzheimer' disease diagnosis. These proposals included revisions to the nearly 30-year-old NINDS-ADRDA criteria for Alzheimer's diagnosis and added criteria for diagnosis of Mild Cognitive Impairment (MCI) due to Alzheimer's disease. The same year the American Psychiatric Association proposed new criteria for major and minor neurocognitive disorders (the entities previously known as dementia and mild cognitive impairment, respectively). These new criteria reflect the research and clinical advances in identifying mild cognitive impairment and offer new opportunities for prevention, treatment, and management of neurodegenerative conditions. A major focus of this book is on the mild cognitive impairment prodrome of the common dementias. In addition to discussing the most common neurodegenerative conditions, many rare neurodegenerative conditions are highlighted. Most chapters include an autopsy-confirmed case presentation from the authors' files. Following the case presentation, those chapters present current diagnostic criteria, epidemiology, neuropathology/neurophysiology, genetics, neuroimaging studies as relevant, associated clinical features, differential neuropsychological features and possible interventions for each disorder. The pace of change in research and practice in the field of normal cognitive aging and dementia is increasing almost as fast as the median age of the population. The massive baby boom population bubble is currently entering the age of risk for neurodegenerative conditions. Neuropsychologists will play a major role in refining and applying these diagnoses, and in developing, testing, and refining interventions for these diagnoses, and in caring for this population. This book is intended to prepare neuropsychologists and others interested in neuropsychology to serve this fastest growing segment of our population.

Cognitive Impairment Therapy Momentum In The Continuum Of Life

Author : Artemissia-Phoebe Nifli
ISBN : 9782889665723
Genre : Science
File Size : 77. 87 MB
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Mild Cognitive Impairment Neuropsychological Profile

Author : Davide M. Cammisuli
ISBN : 8890850256
Genre : Medical
File Size : 68. 94 MB
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Living With Mild Cognitive Impairment

Author : Nicole D. Anderson
ISBN : 9780199764822
Genre : Health & Fitness
File Size : 66. 75 MB
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This book is for individuals with mild cognitive impairment (MCI), their loved ones, and health care professionals who care for these patients. The text is loaded with up-to-date, scientifically substantiated knowledge about what MCI is, how it affects people, and how to take a proactive approach to health and wellbeing for living with MCI.

Coping With Mild Cognitive Impairment Mci

Author : Mary Jordan
ISBN : 9781787750913
Genre : Self-Help
File Size : 36. 93 MB
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Adults are being increasingly diagnosed with Mild Cognitive Impairment (MCI), and this book provides strategies for concerned individuals to help slow the onset of the condition. Around 50% of adults with MCI go on to develop dementia, but research shows that self-help through early intervention and preventative measures can hugely slow this down. The self-help measures in this book include memory aids, health and lifestyle changes, activities, therapies and technological aids. All of them are known to improve cognition and can be incorporated into daily life. Every measure is firmly based in current research, and this book is also applicable to those with early-stage dementia wishing to delay the onset of more severe cognitive impairment. Given the paramount importance of early intervention to prevent cognitive impairment worsening, this book is essential reading for any older individual wanting the best strategies to help with how to do this in practice.

Mild Cognitive Impairment

Author : Holly A. Tuokko
ISBN : 9781000037852
Genre : Psychology
File Size : 71. 14 MB
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The Classic Edition of this foundational text includes a new preface from Holly A. Tuokko, examining how the field of Mild Cognitive Impairment (MCI) has developed since first publication. Bringing together research from multiple studies and perspectives from various countries, the volume identifies MCI as an important clinical transition between normal aging and the early stages of Alzheimer's disease (AD). The up-to-date preface highlights the expansion in research, examining the benefits of various pharmacological, cognitive and behavioral approaches to intervention. Influenced by recent findings in neuroplasticity across the lifespan, the book recognizes the importance of intervention at the earliest stages of the decline trajectory. It revisits the contested diagnostic approaches for MCI as well as the varying prevalence of MCI internationally, yet points to the need for further longitudinal studies to fully understand the condition. Mild Cognitive Impairment continues to provide a comprehensive resource for clinicians, researchers and students involved in the study, diagnosis, treatment and rehabilitation of people with MCI.

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