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Cell Surface Receptors

Author : K. Christopher Garcia, Ph.D
ISBN : 9780080493794
Genre : Science
File Size : 25. 48 MB
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Cell Surface Receptors contains an extensive discussion of cell surface receptors in 11 chapters by experts in their field. As cell surface receptors are involved in almost every aspect of signaling throughout the body, the topic has been of high interest in the community in recent years. Selected Contents: Structures of Axon Guidance Molecules and Their Neuronal Receptors Shared Cytokine Signaling Receptor NKG2D and Related Immunoreceptors Inonotropic Glutamat Receptor Recognition and Activation Chemotaxis Receptors and Signaling

Cell Surface Receptors

Author : K. Christopher Garcia
ISBN : 9780120342686
Genre : Science
File Size : 39. 4 MB
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Cell Surface Receptors contains an extensive discussion of cell surface receptors in 11 chapters by experts in their field. As cell surface receptors are involved in almost every aspect of signaling throughout the body, the topic has been of high interest in the community in recent years. Selected Contents: -Structures of Axon Guidance Molecules and Their Neuronal Receptors -Shared Cytokine Signaling Receptor -NKG2D and Related Immunoreceptors -Inonotropic Glutamat Receptor Recognition and Activation -Chemotaxis Receptors and Signaling

Cell Surface Receptors A Short Course On Theory And Methods

Author : Lee E. Limbird
ISBN : 0792338391
Genre : Medical
File Size : 28. 47 MB
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Cell Surface Receptors: A Short Course on Theory and Methods, Second Edition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.

Cell Surface Receptors

Author : Lee E. Limbird
ISBN : 0387230696
Genre : Medical
File Size : 46. 59 MB
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Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest. The study of receptors has changed considerably over the period of the publication of the three editions of this book. The cloning of several genomes makes it unlikely that preparations of receptors now or in the future will arise from their purification as trace proteins from native tissues, but rather from a myriad of molecular approaches. Nonetheless, understanding the molecular mechanisms and ultimately the in vivo biology of these receptors means that investigators will engage in molecular, cellular and ultimate in vivo strategies. It should be of value to investigators who want to identify, characterize and understand the biology of a receptor of interest.

Nanomagnetic Actuation Of Cell Surface Receptors

Author : Jon Dobson
ISBN : 1466591218
Genre : Medical
File Size : 23. 87 MB
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The manipulation and control of cells and sub-cellular structures through magnetic nanoparticle-based actuation is a relatively new technique that has led to novel and exciting biomedical applications. Nanomagnetic actuation is being used in laboratory studies of stem cells to determine how these mechanical cues can be used to control stem cell differentiation for regenerative medicine applications. This book explores this rapidly expanding field. It will interest industry bioscientists and biomedical engineers as well as academics in cellular biomechanics, cell and tissue engineering, and regenerative medicine.

Cell Surface Receptors

Author : Garth L. Nicolson
ISBN : UOM:39015004410257
Genre : Binding sites (Biochemistry)
File Size : 55. 61 MB
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Cell Surfaces And Malignancy

Author :
ISBN : PURD:32754081178430
Genre : Carcinogenesis
File Size : 88. 52 MB
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Pulmonary Apud Cell Surface Receptors

Author : Frank C. Kelly
ISBN : WISC:89105689475
Genre : Pulmonary circulation
File Size : 40. 35 MB
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Reaction And Aggregation Dynamics Of Cell Surface Receptors

Author : Michelle Dong Wang
ISBN : UOM:39015033121933
Genre :
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Cell Surface Grp78 A New Paradigm In Signal Transduction Biology

Author : Salvatore V. Pizzo
ISBN : 9780128123522
Genre : Science
File Size : 33. 51 MB
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Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative

Library Of Congress Subject Headings

Author : Library of Congress
ISBN : WISC:89116883216
Genre : Subject headings, Library of Congress
File Size : 39. 3 MB
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Cell Membrane Receptors For Drugs And Hormones

Author : Ralph W. Straub
ISBN : UOM:39015003242198
Genre : Cell Membrane
File Size : 79. 21 MB
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Current Medicinal Chemistry

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ISBN :
Genre :
File Size : 81. 59 MB
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The Extracellular Matrix An Overview

Author : Robert Mecham
ISBN : 3642165559
Genre : Science
File Size : 44. 26 MB
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Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Membrane Receptors And Cellular Regulation

Author : Michael P. Czech
ISBN : UOM:39015009580815
Genre : Cell membranes
File Size : 63. 24 MB
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Cell Surface Labeling

Author : Robert P. Becker
ISBN : WISC:89031210396
Genre : Cell membranes
File Size : 21. 41 MB
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Cell Communication And Cell Signaling

Author : SANGAM MISHRA
ISBN :
Genre : Science
File Size : 53. 94 MB
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1. Introduction 2. Molecular Therapy 3. Bacterial signal transduction system 4. Bacterial Signal Transduction Two-Component Regulatory Systems (TCS) and Extra cytoplasmic Function (ECF) σ Factors 5. Stress response 6. Two component receptors 7. Two-component signal transduction systems 8. Summary of useful methods for two-component system research 9. Two component systems in the spatial program of bacteria 10. Rewiring Bacteria, Two Components signal Transduction at a Time; 11. Chemotaxis via chemoreceptor 12. Signal Transduction in Eukaryotes 13. Signaling substances 14. Signals and signal Molecules 15. Lipophilic ligands 16. Cell surface receptors 17. G-protein coupled Receptors (GPCR). 18. Receptor Tyrosine Kinases (RTKs). 19. Transforming Growth Factors (TGFb). 20. Hedge hog Receptors. 21. Wnt. Receptors. 22. Notch Receptors. 23. Heterotrimeric G protein in vertebrate vision 24. Cytosolic Receptors 25. Mode of action of RAR–RXR heterodimers 26. Cell Surface Receptors 27. Ligand gated Ion channels 28. G-protein coupled receptors 29. Receptor tyrosine kinases 30. RTK- Ras pathway 31. MAP/ERK kinase pathway 32. Ras-Raf signal cascade 33. GPCR and RTK Combined Activity 34. Role and action of Yeast mating factors 35. TGF beta Signal Transduction 36. Integrins 37. Toll-like receptors 38. Cytokine signal transduction 39. JAK2 kinase and STAT pathway 40. Intracellular receptors 41. Cytoplasmic- in the cytoplasm of the cell 42. Nuclear- in the nucleus of the cell 43. Insulin Receptor activated pathway 44. The kinase p-lates IRS proteins. 45. Notch signaling Path way 46. Hedgehog signal pathway 47. Wnt signaling Pathway 48. Signal transduction Pathways-A General View 49. Osteoclasts vs Osteoblasts 50. Light induced signal transduction 51. Oxidative stress 52. DNA damage induced molecular pathway 53. Peg3/Pw1 Is a Mediator between p53 and Bax in DNA Damage-induced Neuronal Death 54. messengers and Receptor-Transporters 55. Nitric oxide (NO) 56. DIAG 57. ADPCR 58. Effects of cAMP 59. Effect of cGMP 60. Phosphatidyl Inositol generates many second messengers 61. Calmodulin 62. Diacyl glycerol activates protein kinase C 63. Receptor linked Ion channels 64. Structure of a neuronal nAChR 65. Protein Kinases and Phosphatases 66. Phosphatases in cell– matrix adhesion and migration; 67. PK-B 68. Tyrosine phosphatases 69. Decoy receptors 70. Protein kinases drive adaptation responses 71. An oxylipin-dependent signaling pathway controls stomatal defense. 72. Abscisic acid modulates the biotic stress signal in guard cells. 73. Distinct mitogenactivated protein kinase modules regulate biotic and abiotic stresses. 74. Distinct NADPH oxidase isoforms control reactive oxygen species in response to biotic and abiotic stresses. 75. Salicylic acid is a key signaling step required for stomatal defense. 76. Phytochrome induced G-response 77. Plant Tolerance to Biotic Stresses 78. Auxins signaling pathways 79. NO–cytokinin antagonistic interactions 80. Cytokinin Signaling Pathway 81. A doorman in plant cells 82. Guard cell abscisic acid signalling and engineering drought hardiness in plants; 83. Retrograde signaling pathways and chloroplast– mitochondrion cross-talk in higher plant cells 84. Analysis of calcium signaling pathway in Plants 85. Tyrosine phosphorylation in plant cell signaling; 86. Model for signalling processes in the maintenance and/or the differentiation of procambial cells and xylem cell precursors. 87. Herbivore-induced, indirect plant defences 88. Stomatal signaling and movement 89. Plant Regulators 90. Plant Specific mechanism.

Cell Surface Science In Medicine And Pathology

Author : Edwin Nigel Wardle
ISBN : UOM:39015007123626
Genre : Cell membranes
File Size : 88. 58 MB
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Biosynthetic Modulation Of Cell Surface Sialosides

Author : Lara K. Mahal
ISBN : UCAL:C3446822
Genre :
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Matricellular Receptors As Potential Targets In Anti Cancer Therapeutic Strategies

Author : Hervé Emonard
ISBN : 9782889450244
Genre :
File Size : 36. 11 MB
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The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors are defined as (cell-surface) receptors that bind extracellular matrix (ECM) structural proteins and soluble factors dynamically acting on ECM homeostasis. Matricellular receptors mediate numerous signalings from the extracellular environment to cell nucleus and drive main biological functions that are cell growth, survival and migration. Numerous data from the last decade evidence that matricellular receptors are biosensors that allow to a tumor cell answering to microenvironmental variations, and in this sense they are important contributors to tumor cell malignancy. Matricellular receptors represent thus valuable targets for the development of original anti-cancer strategies. Original reports, bibliographic reviews or hypotheses are welcome to improve the basic knowledge of matricellular receptor properties, their spatio-temporal regulation, the dynamic formation of complex receptors and the impact of such interactions on the invasive properties of tumor cells. Biological, biophysical and pharmacological, as well as in silico contributions will be appreciated.

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