biomarkers-of-human-exposure-to-pesticides

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Biomarkers Of Human Exposure To Pesticides

Author : Mahmoud A. Saleh
ISBN : UOM:39015032764485
Genre : Science
File Size : 33. 74 MB
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Explores the role of biomarker data in evaluating the impact of human environmental and occupational exposure to pesticides. Focuses on two types of biomarkers: residue analysis of parent compounds or metabolites and end points representing interactions between xenobiotic and endogenous components. Characterizes the molecular basis of various biomarker methods and examines structure-activity relationships. Surveys biomarker measurement methods currently in use and examines methods for biomarker data analysis and applications of these methods to risk assessment.

Pesticides In The Modern World

Author : Margarita Stoytcheva
ISBN : 9789533074573
Genre : Technology & Engineering
File Size : 46. 12 MB
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The present book is a collection of selected original research articles and reviews providing adequate and up-to-date information related to pesticides control, assessment, and toxicity. The first section covers a large spectrum of issues associated with the ecological, molecular, and biotechnological approaches to the understanding of the biological control, the mechanism of the biocontrol agents action, and the related effects. Second section provides recent information on biomarkers currently used to evaluate pesticide exposure, effects, and genetic susceptibility of a number of organisms. Some antioxidant enzymes and vitamins as biochemical markers for pesticide toxicity are examined. The inhibition of the cholinesterases as a specific biomarker for organophosphate and carbamate pesticides is commented, too. The third book section addresses to a variety of pesticides toxic effects and related issues including: the molecular mechanisms involved in pesticides-induced toxicity, fish histopathological, physiological, and DNA changes provoked by pesticides exposure, anticoagulant rodenticides mode of action, the potential of the cholinesterase inhibiting organophosphorus and carbamate pesticides, the effects of pesticides on bumblebee, spiders and scorpions, the metabolic fate of the pesticide-derived aromatic amines, etc.

Agrindex

Author :
ISBN : CORNELL:31924063043875
Genre : Agriculture
File Size : 66. 53 MB
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Biomarkers And Human Biomonitoring

Author : Lisbeth Knudsen
ISBN : 9781849733373
Genre : Medical
File Size : 26. 56 MB
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Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and currently used in surveillance programs all over the world. This two volume set provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books decribe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume one describes current human biomonitoring programs in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in human exposures to lead and increasing concern from exposure to endocrine disruptors and the genotoxic compound. Biomarkers of specific exposures to a wide range of widely used everyday compounds such as phthalates, PFCs, bisphenol A, brominated flame retardants, PAHs, dioxins, mercury and arsenic are also discussed. Volume two decribes human biomonitoing of exposures to environmental tobacco smoke, mycotoxins, physiological stress, hormone activity, oxidative stress and ionizing radiation, as well as effect biomarkers of hemoglobin adducts, germ cells, micronuclei and individual susceptability. The books will be essential reading for toxicologists, environmental scientists and all those working in the safety and risk assessment of chemicals.

Environmental Health Perspectives

Author :
ISBN : MINN:30000008401865
Genre : Environmental health
File Size : 25. 61 MB
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Miscellaneous Publication

Author :
ISBN : UCR:31210022186884
Genre : Agriculture
File Size : 29. 6 MB
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Proceedings Of The Third National Ipm Symposium Workshop

Author : Sarah Lynch
ISBN : WISC:89058813478
Genre : Pests
File Size : 36. 91 MB
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Hayes Handbook Of Pesticide Toxicology

Author :
ISBN : 9780080922010
Genre : Medical
File Size : 46. 54 MB
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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.

Information Resources In Toxicology

Author : P.J. Bert Hakkinen
ISBN : 9780080534664
Genre : Medical
File Size : 51. 81 MB
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Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added. This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Agricultural Medicine

Author : James E. Lessenger
ISBN : 9780387301051
Genre : Medical
File Size : 77. 39 MB
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Focuses on both treatment and prevention of medical problems in a rural setting Comprehensive reference for family physicians providing care for patients in rural and agricultural areas Presents a practice-based approach

Biomarkers In Toxicology

Author : Ramesh C. Gupta
ISBN : 9780128146569
Genre : Medical
File Size : 55. 37 MB
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Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Reproductive And Developmental Toxicology

Author : Ramesh C. Gupta
ISBN : 0123820332
Genre : Medical
File Size : 58. 9 MB
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Reproductive toxicology is a complex subject dealing with three components—parent, placenta, and fetus—and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife. Provides a complete, integrated source of information on the key risk stages during reproduction and development Includes coverage of emerging science such as stem cell application, toxicoproteomics, metabolomics, phthalates, infertility, teratogenicity, endocrine disruption, surveillance and regulatory considerations, and risk assessment Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis

Biological Monitoring

Author :
ISBN : 9781931504515
Genre : Technology & Engineering
File Size : 23. 37 MB
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This guide covers the general basics of biological monitoring from the perspective of a field industrial hygienist and also constitutes a field manual for the trainee industrial hygienist. The guide is also suitable for undergraduate students because it contains a slide show and question and answer section: twenty case studies and 118-slide PowerPoint presentation on CD are included

Reviews Of Environmental Contamination And Toxicology

Author : George W. Ware
ISBN : 9781461229643
Genre : Science
File Size : 51. 90 MB
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International concern in scientific, industrial, and governmental communi ties over traces of xenobiotics in foods and in both abiotic and biotic en vironments has justified the present triumvirate of specialized publications in this field: comprehensive reviews, rapidly published research papers and progress reports, and archival documentations. These three international publications are integrated and scheduled to provide the coherency essential for nonduplicative and current progress in a field as dynamic and complex as environmental contamination and toxicology. This series is reserved ex clusively for the diversified literature on "toxic" chemicals in our food, our feeds, our homes, recreational and working surroundings, our domestic an imals, our wildlife and ourselves. Tremendous efforts worldwide have been mobilized to evaluate the nature, presence, magnitude, fate, and toxicology of the chemicals loosed upon the earth. Among the sequelae of this broad new emphasis is an undeniable need for an articulated set of authoritative publications, where one can find the latest important world literature pro duced by these emerging areas of science together with documentation of pertinent ancillary legislation. Research directors and legislative or administrative advisers do not have the time to scan the escalating number of technical publications that may contain articles important to current responsibility. Rather, these individuals need the background provided by detailed reviews and the assurance that the latest information is made available to them, all with minimal literature searching.

Herbicides

Author :
ISBN : 9780128236758
Genre : Science
File Size : 24. 62 MB
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Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts addresses contemporary debates on herbicide toxicology. The reader is offered a comprehensive overview of this complex topic, presented by internationally recognized experts. Information presented will inform discussions on the use of herbicides in modern agricultural and other systems, and their potential non-target effects on human populations and various ecosystems. The book covers these matters in concise language appropriate to engage both specialists in the research community and informed persons responsible for legislative, funding, and public health matters in the community at large. The use of herbicides is an essential pillar of modern agricultural production systems. Weeds, if uncontrolled, would reduce crop yield and result in massive economic damage. Recently, the heavy reliance on single herbicides has been linked to the development of weed resistance. To combat resistant weeds, farmers are advised to use a mix of several herbicides and to increase herbicide application rates. As a result, the toxicity of herbicides on human health and the environment has become a controversial topic. Offers a comprehensive overview of herbicide science in modern agricultural systems Addresses the complex problems that can arise from herbicide use and misuse, including weed resistance, pollution, and human health issues Uses recent examples to demonstrate the topical nature of this issue

Pesticides In The Natural Environment

Author : Pardeep Singh
ISBN : 9780323904902
Genre : Science
File Size : 53. 3 MB
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Pesticides in the Natural Environment: Sources, Health Risks, and Remediation presents the direct and indirect impacts of the use of pesticides on the environment, human health, and agriculture. The book explores sustainable alternatives to pesticide use, along with policies for regulations and remediation techniques. Bridging the gap between regulations and the tangible environmental threat, the book proposes practical solutions while also providing important context on the hazards of pesticides. It highlights the influence on climate change, offering a holistic perspective for researchers in environmental science, policymakers, and land managers. The book introduces pesticides and their applications, then goes on to cover their impact on various ecosystems in the natural environment. Health risks are covered, followed by various remediation techniques, such as biological processes, phytoremediation, and chemical treatments. Describes the impact of pesticides on the environment, human health and the food chain as well as regulations and policies to address the impact Presents remediation strategies and techniques for pesticides in a variety of ecosystems, along with potential alternatives Includes case studies to illustrate the proper management of pesticides and intervention

Pesticide Protocols

Author : José L. Martínez Vidal
ISBN : 9781592599295
Genre : Science
File Size : 29. 76 MB
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A comprehensive collection of robust methods for the detection of pesticide compounds or their metabolites useful in food, environmental, and biological monitoring, and in studies of exposure via food, water, air, and the skin or lungs. The readily reproducible methods range from gas and liquid chromatography coupled to mass spectrometry detection and other classic detectors, to capillary electrophoresis and immunochemical or radioimmunoassay methods. The authors have focused on extraction and cleanup procedures, in order to develop and optimize more fullyautomated and miniaturized methods, including solid-phase extraction, solid-phase microextraction, microwave-assisted extraction, and on-line tandem liquid chromatography (LC/LC) trace enrichment, among others. The protocols offer step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Pesticides

Author : Margarita Stoytcheva
ISBN : 9789533075310
Genre : Technology & Engineering
File Size : 45. 77 MB
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Pesticides are supposed to complete their intended function without "any unreasonable risk to man or the environment". Pesticides approval and registration are performed "taking into account the economic, social and environmental costs and benefits of the use of any pesticide". The present book documents the various adverse impacts of pesticides usage: pollution, dietary intake and health effects such as birth defects, neurological disorders, cancer and hormone disruption. Risk assessment methods and the involvement of molecular modeling to the knowledge of pesticides are highlighted, too. The volume summarizes the expertise of leading specialists from all over the world.

Patty S Industrial Hygiene Evaluation And Control

Author : Barbara Cohrssen
ISBN : 9781119816201
Genre : Science
File Size : 84. 15 MB
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Since the first edition in 1948, Patty’s Industrial Hygiene and Toxicology has become a flagship publication for Wiley. During its nearly seven decades in print, it has become a standard reference for the fields of occupational health and toxicology. The volumes on industrial hygiene are cornerstone reference works for not only industrial hygienists but also chemists, engineers, toxicologists, lawyers, and occupational safety personnel. Volume 2 covers Chemical Exposure Evaluation and Control. Along with the updated and revised chapters from the prior edition, this volume has two new chapters: Sensor Technology and Control Banding.

Anticholinesterase Pesticides

Author : Tetsuo Satoh
ISBN : 0470640499
Genre : Science
File Size : 63. 32 MB
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This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology. The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.

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