beyond-sleep

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Beyond Sleep

Author : Willem Frederik Hermans
ISBN : 9781468303759
Genre : Fiction
File Size : 63. 93 MB
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The young Dutch geologist Alfred Issendorf is determined to win fame for making a great discovery. To this end he joins a small geological expedition, which travels to the far North of Norway, where he hopes to prove a series of craters were caused by meteorites, but ultimately realizes he's more likely to drown in a fjord or be eaten by parasites. Unable to procure crucial aerial photographs, and beset by mosquitoes and insomnia in his freezing leaky tent, Alfred becomes increasingly desperate and paranoid. Haunted by the ghost of his scientist father, unable to escape the looming influence of his mother, and anxious to complete the thesis that will make his name, he moves toward the final act of vanity which will trigger a catastrophe. A deadpan comedy often subtly calling up the works of Heller or Vonnegut at their best, Beyond Sleep is a unique and illuminating examination of how hard it is to be a true pioneer in the modern world. Beyond Sleep is a masterpiece.

Beyond Sleep

Author : BR Raksun
ISBN : 9783739605050
Genre : Fiction
File Size : 55. 88 MB
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"I am here! Don't worry! We have great doctors and excellent equipments. We have needed undaunted courage. We fight with death. Come! I will save you. You will have secured life."Lena has been assaulted and she is hit hard. Now she is fighting for life. Destiny is cruel for me, Lena thought. Lena is voracious and unquenchable reader of news around the world.A flash of news reports in her memory is more disturbing. It is more hurting than her health.Where is the place of 'no death'? It is everywhere!One woman was executed in Hama province. It's an area controlled by Islamic State. Her hands and feet are tied with a rope. She is forced to kneel in a pit. She is covered head to toe. She begins to pray out loud as large rocks are seen striking her body.

Sleep Disordered Breathing Beyond Obstructive Sleep Apnea An Issue Of Clinics In Chest Medicine An Issue Of Clinics In Chest Medicine

Author : Carolyn D'Ambrosio
ISBN : 9780323323185
Genre : Medical
File Size : 54. 42 MB
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Dr. Carolyn D'Ambrosio has put together an expert panel of authors covering topics such as: Sleep and Respiratory Physiology in Adults, Sleep and Respiratory Physiology in Children, Asthma, Cystic Fibrosis, Restrictive Lung Disease, Lung Transplantation, Pulmonary Hypertension and Congestive Heart Failure, Neurologic Conditions, Central Congential Hypoventilation Syndrome, and more!

Prevention Screening And Treatments For Obstructive Sleep Apnea Beyond Pap An Issue Of Sleep Medicine Clinics Ebook

Author : Song Tar Toh
ISBN : 9780323655316
Genre : Medical
File Size : 57. 39 MB
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This issue of Sleep Medicine Clinics, edited by Song Tar Toh in collaboration with Consulting Editor, Teofilo Lee-Chiong, is devoted to the Preventing, Screening, and Treatments for Obstructive Sleep Apnea, beyond Positive Airway Pressure (PAP). Topics covered in this issue include: Prevention and Screening of Obstructive Sleep Apnea (OSA); Anatomical and Physiologic Considerations in Surgical Treatment for OSA; Medical and Surgical Options for Weight Management in OSA; Positional Therapy for OSA; Oral Appliances in Adults and Pediatrics; Myofunctional Therapy for OSA; Drug-induced Sleep Endoscopy in Treatment Options Selection; Establishing a Patent Nasal Passage in OSA; Palatal Surgery: From Ablation to Reconstruction; Volumetric Tongue Reduction Surgery in Clinical Practice; Transoral Robotic Surgery for OSA; Genioglossus Advancement and Hyoid Surgery; Maxillomandibular Rotational Advancement: Airway, Aesthetics, and Angle Considerations;

Relativism And Beyond

Author : Yoav Ariel
ISBN : 9004109307
Genre : Philosophy
File Size : 60. 76 MB
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A collection of essays in which philosophers of widely different interests grapple with the problem of the relative and the absolute in philosophy and religion. A concluding article tries to advance beyond the simple antithesis to a more sophisticated and adequite conception.

Insomnia And Beyond Exploring The Therapeutic Potential Of Orexin Receptor Antagonists

Author : Michel Alexander Steiner
ISBN : 9782889193301
Genre :
File Size : 46. 31 MB
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Orexin/hypocretin neuropeptides, produced by a few thousand neurons in the lateral hypothalamus, are of critical importance for the control of vigilance and arousal of vertebrates, from fish to amphibians, birds and mammals. Two orexin peptides, called orexin-A and orexin-B, exist in mammals. They bind with different affinities to two distinct, widely distributed, excitatory G-protein- coupled receptors, orexin receptor type 1 and type 2 (OXR-1/2). The discovery of an OXR mutation causing canine narcolepsy, the narcolepsy-like phenotype of orexin peptide knockout mice, and the orexin neuron loss associated with human narcoleptic patients laid the foundation for the discovery of small molecule OXR antagonists as novel treatments for sleep disorders. Proof of concept studies from Glaxo Smith Kline, Actelion Pharmaceuticals Ltd. and Merck have now consistently demonstrated the efficacy of dual OXR antagonists (DORAs) in promoting sleep in rodents, dogs, non-human primates and humans. Some of these antagonists have completed late stage clinical testing in primary insomnia. Orexin drug discovery programs have also been initiated by other large pharmaceutical companies including Hoffmann La Roche, Novartis, Eli Lilly and Johnson & Johnson. Orexins are increasingly recognized for orchestrating the activity of the organism’s arousal system with appetite, reward and stress processing pathways. Therefore, in addition to models of insomnia, pharmacological effects of DORAs have begun to be investigated in rodent models of addiction, depression and anxiety. The first clinical trials in diabetic neuropathy, migraine and depression have been initiated with Merck’s MK-6096 (www.clinicaltrials.gov). Whereas the pharmacology of DORAs is established for their effects on wakefulness, pharmacological effects of selective OXR-1 or OXR-2 antagonists (SORAs) have remained less clear. From an evolutionary point of view, the OXR-2 was expressed first in most vertebrate lineages, whereas the OXR-1 is believed to result from a gene duplication event, when mammals emerged. Yet, both receptors do not have redundant function. Their brain expression pattern, their intracellular signaling, as well as their affinity for orexin-A and orexin-B differs. During the past decade most preclinical research on selective OXR-1 antagonism was performed with SB-334867. Only in recent years, other selective OXR-1 and OXR-2 antagonists with optimized selectivity profiles and pharmacokinetic properties have been discovered, and phenotypes of OXR-1 and OXR-2 knockout mice were described. The present Research Topic (referred to in the Editorial as “special topics issue”) comprises submissions of original research manuscripts as well as reviews, directed towards the neuropharmacology of OXR antagonists. The submissions are preclinical papers dealing with dual and/or selective OXR antagonists that shed light on the differential contribution of endogenous orexin signaling through both OXRs for cellular, physiological and behavioral processes. Some manuscripts also report on convergence or divergence of DORA vs. SORA effects with phenotypes expressed by OXR-1 or OXR-2 knockout animals. Ultimately these findings may help further define the potential of DORAs and SORAs in particular therapeutic areas in insomnia and beyond insomnia.

Journey To Awareness And Beyond

Author : Liana Mattulich MD
ISBN : 9781469102122
Genre : Self-Help
File Size : 62. 57 MB
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An enriched view of personal reality drawing from medical and theoretical sciences as well as the esoteric, combining modern experimental science with ancient wisdom which provide keys to the physiology of happiness: Anatomy and Physiology of Mind-Body concepts and the Body Energy Spectrum, Consciousness and the Mind, Dimensional reality, personal reality and time, Spiritual evolution and the soul, Happiness as a self-regulated mind and physiology. A reading experience with an open perspective from human life and mind -- to matter and energies. The book describes for a layman or a professional the weaving of metaphors, exercises and scientific procedures which promote joy in life and the realization of inner freedom. Comprehensive references of both scientific research and empirical experience are provided. Experience proven approaches to joy of well-being of body and mind: subtle energies and Energy Psychology, Meridian physiology in Eastern & Western health practices; Understanding the self, personal direction, goals, and change; Psychology of success, intention, High Will, imagery, inspiration and motivation. Learn leadership qualities, communication skills, assertiveness, and Responsible Open Self-Expression used in managing personal relationships. This is the only book that amalgamates scientific technology with ancient wisdom practices in an integrated system of self-transformation going beyond intellectual and philosophical information alone. More information: www.JourneyToAwareness.org -OR- www.InnerKeys.info

Grammar And Beyond Level 2 Teacher Support Resource Book With Cd Rom

Author : CAMBRIDGE UNIV PR
ISBN : 9781107676534
Genre : Foreign Language Study
File Size : 36. 90 MB
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Based on extensive research, Grammar and Beyond ensures that students study accurate information about grammar and apply it in their own speech and writing. The Grammar and Beyond Teacher Support Resource Book with CD-ROM, Level 2, provides suggestions for applying the target grammar to all four major skill areas, helping instructors facilitate dynamic and comprehensive grammar classes; an answer key and audio script for the Student's Book; a CD-ROM containing ready-made, easily scored Unit Tests, as well as 32 PowerPoint® presentations to streamline lesson preparation and encourage lively heads-up interaction.

Sleep Memory And Learning An Issue Of Sleep Medicine Clinics E Book

Author : Robert Stickgold
ISBN : 9781455709540
Genre : Medical
File Size : 32. 27 MB
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This issue dives into the study of sleep function, particularly as it relates to memory and cognition. Any clinician who sees patients with sleep disorders, or in particular any sleep medicine specialist, will find this information enlightening and invaluable, as it discusses the current state of understanding of how sleep affects humans’ waking cognitive functions. These review articles describe the research that has taken place, and the lessons that can be taken away from them, so that clinicians can confidently advise their patients on the functional importance of adequate sleep, and recognize cognitive symptoms of inadequate sleep. Articles discuss such topics as animal and human research on sleep and memory, various imaging techniques to describe brain activity during sleep, and the role of dreams.

Sleep Medicine And Dentistry An Issue Of Dental Clinics E Book

Author : Ronald D. Attanasio
ISBN : 9781455743971
Genre : Medical
File Size : 75. 62 MB
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Sleep Medicine is a relatively new medical specialty that has demonstrated its clear relevance to the practice of many other specialties, and dentistry is no exception. This issue of Dental Clinics of North America includes articles that address aspects of sleep medicine most relevant to the dentist, such as bruxism, breathing disorders, and Insomnia.

Beyond Botox

Author : Ben Kaminsky
ISBN : 9780446561525
Genre : Health & Fitness
File Size : 64. 63 MB
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Sexy and ageless skin is possible for a woman at any age--and she doesn't have to resort to invasive treatments like Botox to get it-as long as she cares for her skin properly, says Ben Kaminsky, founder of B. Kamins, Chemist and leading authority in helping women's skin look healthy and beautiful. In Beyond Botox, Kaminsky provides a groundbreaking 7-step plan to help skin look younger and sexier...without Botox or surgical procedures. The book's plan is based in science and targeted specifically to women who are searching for a common-sense alternative to eating fish 6 days a week (a la Perricone). This plan includes scientific secrets on how exercising too vigorously can rob your skin of vitality; how getting 8 hours' sleep for a week will take years off your skin; and how using the right amount of moisturizer (and the right weight of moisturizer) will actually make a difference in how your skin looks and feels. Beyond Botox will not advocate use of only B. Kamins products. Kaminsky will talk about popular products and how to find creams that will make a difference on your skin type. B. Kamins, Chemist has established itself as THE skincare brand for women in midlife, and this book will establish itself as THE book for women who want vital-looking skin in midlife and beyond.

Beyond Cell Memory

Author : Grace J. Scott
ISBN : 9781462037124
Genre : Body, Mind & Spirit
File Size : 22. 39 MB
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In 2002, author Grace J. Scott began to receive channeled material from the beyond and to publish the results. This latest book of such material was delivered by souls selected by Creator to deliver His message—that He is the origin of all that is—to the world. All of creation began with a cell of Creator, and this single individual cell of His energy contains an exact copy of His DNA and cell memory. That is how we are all connected—how we are all one. Beyond Cell Memory presents the channeled material in simple language so that all who read it may understand such mysteries as how souls and bodies were created. As humans evolved physically, our form, size, and intellect were enhanced by beings of higher intellect and spiritual vibration from other universes; these same beings are now surrounding and protecting Earth. Famous people—Dr. Sigmund Freud, Carl Jung, and Edgar Cayce—channeled material that covers dreams, homosexuality, abortion, and suicide. Isaac Newton and Galileo Galilei channeled material that suggests that DNA and cell memory connect us to souls of other universes and the Creator of all that is. What we, as souls, do on our planet is known by and impacts other planets containing souls. Each soul contains DNA and cell memory from Creator, and this same soul exists regardless of the number of lives lived. With imminent cataclysmic Earth changes, we must learn how to clear our cell memory of trauma.

Circadian Rhythms

Author : Michael Young
ISBN : 0080455409
Genre : Science
File Size : 89. 43 MB
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The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences. Circadian Rhythms contains an extensive discussion of genetic and biochemical aspects of circadian rhythms. In this volume organisms such as neurospora, bacteria, drosophila, arabidopsis and mammals are covered. Included are methods in genetics, transcriptional and post-transcriptional regulation, tissue culture, and populations are discussed in detail. * One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences

Sleep In Children And Adolescents An Issue Of Pediatric Clinics E Book

Author : Judith Owens
ISBN : 9781455712366
Genre : Medical
File Size : 20. 85 MB
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Pediatric and Adolescent Psychopharmacology is reviewed in this issue of Pediatric Clinics, guest edited by Drs. Dilip Patel, Donald Greydanus, and Cynthia Feucht. Authorities in the field have come together to pen articles on Therapy in the Age of Pharmacology: Point-Counterpoint, Principles of Pharmacology and Neurotransmission, Complementary and Alternative Medicine in Pediatric Mental Health, Psychopharmacology of Anxiety Disorders, Psychopharmacologic Control of Aggression and Violence, Autistic Spectrum Disorders, Attention Deficit Hyperactivity Disorder, Psychopharmacology of Anorexia and Bulimia Nervosa, Psychopharmacology of Obesity, Psychopharmacology of Depression, Psychopharmacology of Pediatric Bipolar Disorders, Cognitive-Adaptive Disabilities, Psychopharmacology of Schizophrenia, Management of Psychotic States Induced by Medical Conditions, Substance Use and Abuse, Psychopharmacology of Tic Disorders, and Pharmacology of Sleep Disorders.

Genetics And Sleep An Issue Of Sleep Medicine Clinics E Book

Author : Allan Pack
ISBN : 9781455712007
Genre : Medical
File Size : 90. 2 MB
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This issue describes in detail the most current thinking on the way genes affect and determine sleep patterns, behaviors, disorders and needs. Sleep researchers continue to study genetic markers that may someday lead to a personalized approach to treatment of sleep disorders. The genetics of restless legs syndrome, narcolepsy, circadian rhythm disorders, obstructive sleep apnea, parasomnias, and insomnia are discussed. A solid understanding of the role genetics and molecular biology play in sleep will aid clinicians in diagnosing and treating these disorders, as well as advising their patients.

Beyond Death S Door

Author : Gerald Wheeler
ISBN : 9780828024747
Genre : Religion
File Size : 42. 1 MB
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People have been trying to comprehend death for millennia-nearly every culture known to humanity has put forth some theory of what happens to a person after life. But who knows what really happens? Not one of us alive today has experience death firsthand.Although the Bible has much to say on the subject of death, there are several conflicting views of the afterlife. Which one is actually biblical? And which view does science support?Beyond Death's Door examines the Bible and science for the truth about the afterlife--and discovers that one of the first lies told humanity has been taught as gospel truth for thousands of years.

The Oxford Handbook Of Infant Child And Adolescent Sleep And Behavior

Author : Amy R. Wolfson
ISBN : 9780199873647
Genre : Psychology
File Size : 45. 42 MB
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Since the early 20th century, parenting books, pediatricians, and other health care providers have dispensed recommendations regarding children's sleep that frequently involved behavioral and educational approaches. In the last few decades, however, psychologists and other behavioral scientists and clinicians have amassed a critical body of research and clinical recommendations regarding developmental changes in sleep, sleep hygiene recommendations from infancy through adolescence, and behaviorally oriented treatment strategies for children and adolescents. The Oxford Handbook of Infant, Child, and Adolescent Sleep and Behavior provides a comprehensive and state-of-the-art review of current research and clinical developments in normal and disordered sleep from infancy through emerging adulthood. The handbook comprises seven sections: sleep and development; factors influencing sleep; assessment of sleep and sleep problems; sleep challenges, problems, and disorders; consequences of insufficient sleep; sleep difficulties associated with developmental and behavioral risks; and prevention and intervention. Written by international experts in psychology and related disciplines from diverse fields of study and clinical backgrounds, this handbook is a comprehensive resource that will meet the needs of clinicians, researchers, and graduate students with an interest in the multidisciplinary and emerging field of child and adolescent sleep and behavior.

Beyond Your Life Is Poetry Every Motion Every Pulse Is Poetry In The Making

Author : Donell Jackson
ISBN : 9781469170633
Genre : Poetry
File Size : 61. 91 MB
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I am a writer of many different areas, Im currently working on my next book called How A Man Should Treat His Woman This book will have a lot of thing to take a relationship to another level as well as it will have a little surprise at the end for all my reader; Leading into my next following book. I appreciate all the support from all my fellow readers and I will continue to bring you more things to read and open your eyes to different things that life holds. I dont mind helping out up and coming poets, so if you would like to have a section in my next poetry book in the amateur section. You can contact me at [email protected] I wouldnt mind featuring you if you think you have what it takes and would like to get one of your poems out contact me with your contact information. Contact is not for royalties but for advertisement purposes only. Thank you!

Principles And Practice Of Sleep Medicine E Book

Author : Meir H. Kryger
ISBN : 9781437727739
Genre : Medical
File Size : 32. 28 MB
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Principles and Practice of Sleep Medicine, 5th Edition, by Meir H. Kryger, MD, FRCPC, Thomas Roth, PhD, and William C. Dement, MD, PhD, delivers the comprehensive, dependable guidance you need to effectively diagnose and manage even the most challenging sleep disorders. Updates to genetics and circadian rhythms, occupational health, sleep in older people, memory and sleep, physical examination of the patient, comorbid insomnias, and much more keep you current on the newest areas of the field. A greater emphasis on evidence-based approaches helps you make the most well-informed clinical decisions. And, a new more user-friendly, full-color format, both in print and online, lets you find the answers you need more quickly and easily. Whether you are preparing for the new sleep medicine fellowship examination, or simply want to offer your patients today's best care, this is the one resource to use! Make optimal use of the newest scientific discoveries and clinical approaches that are advancing the diagnosis and management of sleep disorders.

Beyond Heaven And Earth

Author : Steven H Propp
ISBN : 9781469752778
Genre : Fiction
File Size : 82. 55 MB
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Have you ever wondered what happens to us when we die? What if you really HAD to know? When tragedy strikes the family of young Jobran Winter, he is forced to confront these questions directly. Undertaking a feverish "Quest," he explores various branches of Christianity; Judaism; Islam; Hinduism; Buddhism; Sikhism, as well as the religions of China and Japan. His search encompasses the New Age, Reincarnation, Spiritism and Psychical Research. Attending channeling sessions and sances, investigating haunted houses and Near-Death Experiences, he examines spiritual traditions ranging from Swedenborg to Scientology, from Jodo Shinshu to the Jehovah's Witnesses. Finally, the Quest brings him into direct contact with Hospice work; physical disability; child abandonment; abortion; suicide; euthanasia, and even cold-blooded murder. Encounter the doctrines of Purgatory & Predestination, Universalism & Annihilationism, as you journey in a novel that will make you reexamine your ideas about religion, skepticism, love, death and LIFE.

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