plasticity in the adult brain from genes to neurotherapy progress in brain research

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Plasticity In The Adult Brain From Genes To Neurotherapy

Author : M.A. Hofman
ISBN : 008049773X
Genre : Science
File Size : 56. 99 MB
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In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.

Art And The Brain

Author : Amy Ione
ISBN : 9789004322998
Genre : Art
File Size : 64. 64 MB
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In her new book Art and the Brain: Plasticity, Embodiment and the Unclosed Circle, Amy Ione offers a profound assessment of our ever-evolving view of the biological brain as it pertains to embodied human experience.


Author : Joost Verhaagen
ISBN : 0080922961
Genre : Medical
File Size : 53. 81 MB
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This book focuses on the exciting recent progress in restorative neurology and neuroscience. The book includes chapters on major neurodegenerative disorders of the brain and the visual system, including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, macular degeneration, retinitis pigmentosa, glaucoma, spinal cord trauma, and multiple sclerosis. The primary goal of the book is to give an overview of new developments in translational research and in potential therapeutic strategies, including stem cell therapy, immunotherapy, gene therapy, pharmacotherapy, neuroprostheses and deep brain stimulation. * Provides the reader with a unique overview over all aspects of new advances in the therapy of neurological and psychiatric disorders * Covers all levels of biological organization including novel molecular and cellular targets, electrophysiological, anatomical and behavioural substrates of neurodegeneration and the application of whole brain in vivo imaging * Broad focus with contributions by the top scientists worldwide in the respective disciplines

Event Related Dynamics Of Brain Oscillations

Author : Christa Neuper
ISBN : 0080465595
Genre : Medical
File Size : 44. 32 MB
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Research on brain oscillations and event-related electroencephalography (EEG) and event-related (de-) synchronization (ERD/ERS) in particular became a rapidly growing field in the last decades. A large number of laboratories worldwide are using ERD/ERS to study cognitive and motor brain function and the importance of this tool in neurocognitive research is widely recognized. This book is a summary of the most current research, methods, and applications of the study of event-related dynamics of brain oscillations. Facing the rapid progress in this field, it brings together, on the one side, fundamental questions of the underlying events, which still remain to be clarified and, on the other side, some of the most significant novel findings, which point to the key topics for future research. In particular, the chapters of this volume cover the neurophysiological fundamentals and models (Section I), new methodological approaches (Section II), current ERD research related to cognitive (Section III) and sensorimotor brain function (Section IV), invasive approaches and clinical applications (Section V), and novel developments of EEG-based brain-computer interfaces and neurofeedback (Section IV).

Reprogramming The Brain

Author : Aage R. Moller
ISBN : 0080465919
Genre : Science
File Size : 22. 6 MB
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The brain is plastic and it can change its function to adapt to changing demands of various kinds. The brain can also re-organize and change its function to better utilize its resources when parts of the brain have been damaged through injuries and diseases. This means that the brain is not “hard wired but can be reprogrammed when needed. This book describes different aspects of how the plasticity can become activated and how it can benefit the individual person. This book provides in-depth coverage of many important aspects of neural plasticity and how it applies to trauma, including strokes and disorders of the central nervous system that affect memory and cognition. The book also discusses how neural plasticity is involved in aphasia, pain and tinnitus. The roles of neural plasticity in motor rehabilitation and in adaptation to prostheses such as cochlear and cochlear nucleus implants are also topics of the book. * Provides in-depth coverage of many important aspects of neural plasticity and how it applies to trauma, including strokes and disorders of the central nervous system that affect memory and cognition * Discusses how neural plasticity is involved in aphasia, pain and tinnitus * Explains the roles of neural plasticity in motor rehabilitation and prosthesis such as cochlear and cochlear nucleus implants

Vasopressin And Oxytocin From Genes To Clinical Applications

Author : D. Poulain
ISBN : 0080522823
Genre : Science
File Size : 82. 69 MB
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The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system. Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.

Brain Mechanisms For The Integration Of Posture And Movement

Author :
ISBN : 0080494080
Genre : Medical
File Size : 73. 1 MB
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Brain Mechanisms for the Integration of Posture and Movement

Ngf And Related Molecules In Health And Disease

Author : L. Aloe
ISBN : 0080497500
Genre : Science
File Size : 39. 6 MB
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The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.

The Roots Of Visual Awareness

Author : C.A. Heywood
ISBN : 0080498108
Genre : Psychology
File Size : 27. 32 MB
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The present volume was assembled in honor of Professor Alan Cowey FRS, and attempts to embrace his wide range of research interests in visual neuroscience. It is divided into four sections. The first contains a group of papers dealing with different fundamental aspects of the visual system, including the control and monitoring of eye movements. The second is concerned with the functional organization of cortical visual areas and their role in visual perception and visually guided action. The third addresses issues concerning color and motion perception, along with broader questions of visual attention; and the effects of selective brain damage on these different aspects of visual experience. The fourth and final section of the volume deals explicitly with questions relating to visual awareness, with particular emphasis on 'blindsight', a topic on which Alan Cowey has worked extensively in recent years, both in humans and in monkeys.

Gonadotropin Releasing Hormone Molecules And Receptors

Author : I.S. Parhar
ISBN : 0080524761
Genre : Science
File Size : 87. 59 MB
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This volume summarizes the evolution and physiology of GnRH molecules and receptors, and provides insight as to how social behavior influences cellular and molecular events in the brain from a comparative perspective. The chapters in this volume are divided into three major sections: Development and Cell Migration, GnRH Receptors, Physiology and Regulation. The review papers arose primarily from presentations made at the Second International Symposium on the Comparative Biology of GnRH, held in Penang, Malaysia, June 2-4, 2001; a satellite symposium in conjunction with the XIV International Congress of Comparative Endocrinology, Sorrento, Italy. In addition, leading neuroscientists doing cutting-edge research in the field of GnRH were invited as authors to make this volume a valuable reference.

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